Pesquisa sobre: RETINOBLASTOMA-BINDING PROTEIN 4 
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Descritor Inglês:   Retinoblastoma-Binding Protein 4 
Descritor Espanhol:   Proteína 4 de Unión a Retinoblastoma 
Descritor Português:   Proteína 4 Ligante de Retinoblastoma 
Categoria:   D08.811.277.087.520.500.775
D08.811.277.087.520.750.775
D08.811.600.620.775
D08.811.600.795.775
D12.644.360.024.328.600
D12.776.157.057.158.600
D12.776.476.024.414.600
D12.776.580.219.200.500
D12.776.660.769.600
Definição Inglês:   A retinoblastoma-binding protein that is involved in CHROMATIN REMODELING, histone deacetylation, and transcription repression. Although initially discovered as a retinoblastoma binding protein it has an affinity for core HISTONES and is a subunit of chromatin assembly factor-1 where it plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. 
Nota Histórica Inglês:   2010 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   53592 
Identificador Único:   D056505 

Ocorrência na BVS: 		 

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